Air Fryer Beef Sandwiches

Section: Satisfying Main Dishes for Every Occasion

These Air Fryer Roast Beef Sandwiches bring together melty Swiss cheese, tender deli roast beef, and a creamy tangy sauce in warm toasted buns. Using the air fryer makes them fast and mess-free, ideal for busy nights or satisfying lunches. You can tweak the sauce to your taste or even serve open-faced. They work beautifully with coleslaw, pickles, or kettle chips on the side. Whether it is for game day or a casual meal, this sandwich is hearty, cheesy, and full of flavor.

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Published By Ioana
Updated on Tue, 24 Jun 2025 19:51:15 GMT
Two air fryer roast beef sandwiches. Bookmark
Two air fryer roast beef sandwiches. | ioanacooks.com

These air fryer roast beef sandwiches are warm gooey and incredibly satisfying with minimal effort. The combination of tender roast beef Swiss cheese and a tangy creamy sauce packed into a toasted brioche bun makes it a favorite go to for quick lunches or casual dinners

I first threw this together on a hectic school night and now it has become a staple whenever we need something fast comforting and delicious

Ingredients

  • Mayonnaise: adds creaminess and balances heat choose real mayo for the best result
  • Stone ground mustard: brings texture and boldness pick one with visible mustard seeds for extra flavor
  • Prepared horseradish: provides gentle heat go with a refrigerated version for freshness
  • Brioche buns: offer a sweet buttery base opt for fresh soft ones to hold the fillings well
  • Swiss cheese: melts smoothly and brings a mild nutty depth you can also use havarti or provolone
  • Thinly sliced deli roast beef: delivers savory flavor choose a lean cut with some marbling

Step-by-Step Instructions

Make the Sauce:
In a small bowl combine mayonnaise stone ground mustard and prepared horseradish mix until fully blended and smooth
Prep the Buns:
Place the bottom and top halves of the buns inside your air fryer basket optionally line it with foil for easy cleanup spread the prepared sauce onto each bun half covering the entire surface
Add Cheese and Meat:
Place one slice of Swiss cheese on each bun on the bottom buns add about five slices of roast beef making sure to layer evenly
Air Fry the Sandwiches:
Set your air fryer to 370 degrees Fahrenheit cook the sandwiches for 4 to 6 minutes until the cheese melts meat warms through and buns turn golden if tops brown too fast remove them halfway through
Repeat and Serve:
Work in batches if needed depending on your air fryer size repeat the process and serve sandwiches hot with your favorite sides
A roast beef sandwich with cheese and lettuce. Bookmark
A roast beef sandwich with cheese and lettuce. | ioanacooks.com

I love the creamy heat that horseradish adds to this sandwich and it reminds me of when my husband first raved about it after a long day at work we now keep horseradish stocked just for this

Storage Tips

Wrap leftover sandwiches in foil and refrigerate up to two days reheat in the air fryer for a few minutes to bring back the crunch and gooey cheese

Ingredient Substitutions

If you prefer less heat swap horseradish for garlic aioli use dijon instead of stone ground mustard or replace Swiss cheese with provolone or gouda

Serving Suggestions

Pair with potato chips coleslaw or a pickle spear for a deli style lunch or dip into warm au jus for a French dip twist

A sandwich with meat and cheese. Bookmark
A sandwich with meat and cheese. | ioanacooks.com

Cultural Context

Beef sandwiches have long been a comfort food across the United States this air fryer version brings modern convenience to a deli classic while preserving bold hearty flavor

Frequently Asked Questions About Recipes

→ Can I use different types of mustard?

Yes. If stone ground mustard is not your favorite, you can substitute it with Dijon or even leave it out completely depending on your taste.

→ What kind of cheese works best?

Swiss cheese melts beautifully, but Havarti, provolone, or gouda also pair well with the beef.

→ Can I make this open faced?

Yes. Simply reduce the cook time by about a minute when making it open faced in the air fryer.

→ What sauce alternatives can I use?

Try garlic aioli, mayo, BBQ sauce, or a sweeter sauce with added honey or maple syrup. You can also use Horsey Sauce or Arby-Q Sauce.

→ How do I store leftovers?

Keep any leftover sandwiches in an airtight container for up to 2 to 3 days. Reheat gently in the air fryer or oven to avoid sogginess.

→ Can I serve it as a beef dip?

Absolutely. Warm up beef consommé or prepare an au jus gravy packet for dipping.

Air Fryer Beef Sandwiches

Crispy buns filled with roast beef, Swiss cheese, and a tangy spread in minutes using your air fryer.

Time Needed to Prep
10 minutes
Cooking Duration
6 minutes
Overall Time
16 minutes
Published By: Ioana

Category of Recipe: Main Dishes

Preparation Difficulty: Easy to Make

Type of Cuisine: American

Number of Portions: 4 How Many It Serves (4 sandwiches)

Dietary Preferences: ~

Ingredients You'll Need

→ Main Ingredients

Ingredient 01 1 pound thinly sliced deli roast beef
Ingredient 02 4 brioche buns
Ingredient 03 4 slices Swiss cheese

→ Sauce

Ingredient 04 1/4 cup mayonnaise
Ingredient 05 1 tablespoon stone ground mustard
Ingredient 06 1 tablespoon prepared horseradish

Steps to Follow

Step 01

In a small bowl, mix mayonnaise, stone ground mustard, and prepared horseradish until smooth.

Step 02

Place the bottom and top buns in the air fryer basket and spread the sauce on each bun half.

Step 03

Place a slice of Swiss cheese on each bun. Add approximately five slices of roast beef on each bottom bun.

Step 04

Cook in an air fryer at 370°F for 4 to 6 minutes until the meat is warmed and cheese melted. Remove top buns if over-browning.

Step 05

Repeat the process for remaining sandwiches and serve hot.

Extra Tips

  1. Open faced sandwiches require about 1 minute less cook time.
  2. Use foil in the air fryer basket for easier cleanup.
  3. Swap stone ground mustard or horseradish with aioli or mayonnaise based on taste preferences.

Tools You'll Need

  • Air fryer
  • Mixing bowl
  • Spreader or spoon

Allergen Information

Carefully check food labels for allergens and consult an expert if you're uncertain.
  • Contains dairy from Swiss cheese and mayonnaise
  • Contains gluten from brioche buns
  • Contains egg from mayonnaise

Nutritional Information (Per Serving)

Remember, these values are for guidance only and shouldn't replace advice from a professional.
  • Calories Per Serving: 540
  • Total Fat: 28 grams
  • Carbohydrate Amount: 32 grams
  • Protein Amount: 36 grams